I normally don't write reviews but I want everyone to know that these products are not 100% safe. They come with risks just like any other medical product and before using them, you should be cautious and watch for any adverse reactions. So... here's my story. I have 3 dogs, a 16 year old border collie, a 8 month old german shepherd and a 13 year old blue tick. I used this product on all 3 dogs and 15 minutes later my border collie has ataxia and rapid eye movement. In other words he was falling all over the place and his eyes won't focus. I almost immediately washed him with dawn soap and he is still having severe symptoms. The eye movement isn't as severe 24 hours later, but all the other symptoms are still present. Only supportive care can be done at this point. He is getting fluids and we are making sure his body temperature is normal. It breaks my heart. He was a perfectly healthy older dog with only mild aches and pains. I am hoping he pulls through it.