I bought an IS clincal serum which is not cheap. When i opened my bottle, it exploded. I am no stranger to this product so it was either stored in the wrong temp, or i dont know. I am not the brains behind the product, but i emailed dermstore with pics of what it did. I probably lost about 20$ worth of product just from opening up the bottle and they completely ignored my email. That is poor customer service! I will not give my business to companies that don't care about the end user once they got their money.